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Hand and Elbow Center                 Dr. Luther is a fellowship trained Hand and Upper Extremity Surgeon. He earned his BS from the Massachusetts Institute of Technology (MIT) and MD degree from the University of Chicago. He completed his orthopedic surgery residency at Harvard Medical School- training at Massachusetts General Hospital, Brigham & Women's Hospital, Boston Children's Hospital and Beth Israel Deaconess Medical Center. He was a chief resident at Massachusetts General Hospital then went on to pursue a subspecialty fellowship in hand and upper extremity surgery at the Harvard Hand Fellowship in Boston.

Over his career Dr. Luther has published over 20 peer-reviewed papers, several book chapters, and lectured nationally and internationally on hand and upper extremity disorders.  He is the recipient of numerous research and teaching awards and an active member of the American Academy of Orthopaedic Surgeons (AAOS) and American Society for Surgery of the Hand (ASSH). He currently serves on national committees focused on medical education and value-based healthcare delivery. Throughout his career, he has focused on delivering exceptional patient care by combining his interests in education, research and clinical care.

Dr. Luther has a clinical interest in nerve injuries and reconstruction, peripheral nerve surgery, hand and upper extremity fractures, minimally invasive surgery, ligament and tendon disorders, rheumatoid and osteoarthritis, joint replacement, and pediatric hand surgery.  As a collegiate tennis player, Dr. Luther also enjoys caring for athletes with hand and upper extremity injuries, with a focus on early return to play.

His outside interests include value-based healthcare delivery, medical education, health care efficiency and patient-centered quality and outcomes research. In his free time, he enjoys playing tennis, soccer, hiking and traveling the world. He has moved to North Carolina from Boston with his wife, son and dog and enjoy exploring all that the area has to offer.

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Honors and Awards: 

Jun 2017     Best Clinical Research Award - Harvard Combined Orthopaedics Residency

Jun 2016     Chief Resident - Massachusetts General Hospital/Harvard Combined Orthopaedics Residency

Sep 2015     Clinician Scholar Development Program - America Academy of Orthopaedic Surgeons

May 2015    Resident Teaching Award - Harvard Medical School

Mar 2014    Best Poster Award - Adult Hip Reconstruction, American Academy of Orthopedic Surgeons Conference

Oct 2013      Adrian E. Flatt Resident Research Scholarship- American Society of Surgery for the Hand

May 2012    Leon Jacobson Award for Best Oral Presentation - Senior Scientific Session, University of Chicago Pritzker School of Medicine

Apr 2012     Best Abstract - International Congress for Joint Reconstruction Conference

Feb 2012     Best Oral Presentation - Tumor Society, American Academy of Orthopedic Surgeons

Aug 2011    Fentress Research Fellowship - University of Chicago Pritzker School of Medicine

Mar 2011    Best Basic Science Presentation - Huggins Research Symposium, University of Chicago Pritzker School of Medicine

Mar 2011    Best Clinical Presentation - Huggins Research Symposium, University of Chicago Pritzker School of Medicine

Jun 2010     Pritzker Research Fellowship - University of Chicago Pritzker School of Medicine

Memberships & Publications: 

Luther G., Blazar P., Dyer G. Achieving Microsurgical Competency in Orthopedic Residents Utilizing a Self-Directed Microvascular Training Curriculum.  Accepted to JBJS.  Mar 2018

Luther G., Murthy P., Blazar P.  Cost of Immediate Surgery Versus Non-Operative Treatment for Trigger Finger in Diabetic Patients.  Journal of Hand Surgery.  Sep 2016.  PMID: 27671766

Luther G., Miller P., Mahan S., Waters PM., Bae DS.  Decreasing Resource Utilization Using Standardized Clinical Assessment and Management Plans (SCAMPs).  J Pediatric Orthopaedics.  Sep 2016.  PMID: 25887819

Luther G., Lamplot J., Chen X., Rames R., Wagner E., Shen J., Haydon R., He T.C., Luu H.,  IGFBP5 Domains Exert Distinct Inhibitory Effects on the Tumorigenicity and Metastasis of Human Osteosarcoma.  Cancer Letters.  May 2013 PMID: 23665505

Luther G.,  Wagner E., Zhu G., Kang Q., Luo Q., Lamplot J., Bi Y., Luo X., Luo J., Teven C., Shi Q., Kim S., Gao J., Huang E., Rames R., Liu X., Li M., Hu N., Su Y., Chen L., He B.C., Zuo G., Deng Z., Reid R., Luu H., Haydon R., He T.C.  BMP-9 Induced Osteogenic Differentiation of Mesenchymal Stem Cells: Molecular Mechanism and Therapeutic Potential.  Current Gene Therapy.  Mar 2011.  PMID: 21453282

Luther G., Rames R., Wagner E., Zhu G., Luo Q., Bi Y., Kim S., Gao J., Huang E., Yang K., Wang L., Liu X., Li M., Hu N., Su Y., Luo X., Chen L., Luo J., Haydon R., Luu H., Zhou L., He T.C.  Molecular Basis of Differentiation Therapy for Soft Tissue Sarcomas.  Trends in Cancer Research.  Jan 2011

Behzadi S., Luther G., Harris MB., Farokhzad O., Mahmoudi M.,  Nanomedicine for Safe Healing of Bone Trauma: Opportunities and Challenges.  Biomaterials.  Sep 2017

Lamplot J., Luther G., Mawdsley E.L., Luu H.H., Manning D.   Modified Protocol Decreases Surgical Site Infections after Total Knee Arthroplasty.  Journal of Knee Surgery.  Mar 2015.  PMID: 25699629

Lamplot J., Liu B., Zhang W., Wang Z., Luther G., Wagner E., He T.C., Ho S.   Reversibly Immortalized Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype.  Cell Transplantation.  Apr 2014.  PMID: 24800751

Chen X., Luther G., Zhang W., Nan G., Wagner E., Liao Z., Haydon R., Zhou L., Luu H., He T.C.   The E-F Hand Calcium-Binding Protein S100A4 Regulates the Proliferation, Survival and Differentiation of Potential of Human Osteosarcoma Cells.  Cellular Physiology and Biochemistry.  Sep 2013.  PMID: 24217649

Hekman K., Aliaga L., Straus D., Luther G., Chen J., Sampat, Frim D.  Positive and Negative Predictors for Good Outcome After Decompressive Surgery for Chiari Malformation Type 1 as Scored on the Chicago Chiari Outcome Scale.  Neurological Research.  Sep 2012.  PMID: 22781921

Aliaga L., Yassari R., Straus D., Hekman K., Luther G., Chen J., Sampat A., Frim D.   A Novel Scoring System for Assessing Chiari Malformation Type 1 Treatment Outcomes.  Neurosurgery.   Mar 2012 PMID: 21849925

Teven C., Liu X., Hu N., Tang N., Kim S., Huang E., Yang Ki., Li M., Gao J., Liu H., Luther G., Luo Q., Wang L., Rames R., Bi Y., Luo J., Luu H., Haydon R., Reid R., He T.C.  Epigenetic Regulation of Mesenchymal Stem Cells: A Focus on Osteogenic and Adipogenic Differentiation.  Stem Cells and Nuclear Reprogramming.   Jul 2011.  PMID: 21772852

Wagner E., Luther G., Zhu G., Luo G., Shi Q., Kim S., Gao J., Huang E., Gao Y., Yang K., Wang L., Teven C., Luo X., Liu X., Li M., Hu N., Su Y., Bi Y., He B.C., Haydon R., Luu H., He T.C.  Defective Osteogenic Differentiation in the Development of Osteosarcoma.  Sarcoma.  Feb 2011.  PMID: 21437219

Pandey S., Luther G., Umanskiy K., Malhotra G., Rubin M., Fichera A.  Minimally Invasive Pouch Surgery for Ulcerative Colitis.  Is there a Benefit in Staging?  Disease of the Colon and Rectum.  Feb 2011.  PMID: 21304301

Rastegar F., Gao J., Shenaq D., Luo Q., Shi Q., Kim S., Jiang W., Wagner E., Huang E., Gao Y., Shen J., Yang K., He B.C., Chen L., Zuo G., Luo J., Luo X., Bi Y., Liu X., Li M., Nu N., Wang L., Luther G., Luu H., Haydon R., He T.C.  Lysophosphatidic Acid Acyltransferase b (LPAATb) Promotes Tumor Growth of Human Osteosarcoma.  PLoS ONE.  Dec 2010.  PMID: 21152068

He B.C., Gao J., Zhang B., Luo Q., Shi Q., Kim S., Huang E., Gao Y., Yang K., Wagner E., Wang L., Tang N., Luo J., Liu X., Li M., Bi., Shen J., Luther G., Hu N., Zhou Q., Luu H., Haydon R., Zhao Y., He T.C.  Tetrandrine Inhibits Wnt/B-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer.  Molecular Pharmacology.  Oct 2010.  PMID: 20978119

Teply B., Tong R., Jeong S., Luther G., Sherifi I., Yim C., Khademhosseini A., Farokhzad O., Langer R., Cheng J.  The Use of Charge-Coupled Polymeric Microparticles and Micromagnets for Modulating the Bioavailability of Orally Delivered Macromolecules.  Biomaterials.  Dec 2007.  PMID: 18082254

Cheng J., Teply B., Sherifi I., Sung J., Luther G., Gu F., Nissenbaum E., Moreno A., Langer R., Farokhzad O.  Formulation of Functionalized PLGA-PEG Nanoparticles for in Vivo Targeted Drug Delivery.  Biomaterials.  Feb 2007.  PMID: 17055572